Alignment represention: -> The line labled 'iso' is the isostericity base-pair indication. A Star '*' represents the matched location in the seqeunce is a of part a matched isosteric base-pair.A plus symbol '+' represents the matched location is a part of matched non-isosteric base-pair. -> The line labeled 'edge' is the interacting edges. 'W' is for Watson-Crick, 'H' is for Hoogsteen, and 'S' is for sugar edge.Upper case letters are for 'cis' orientation base-pairs while lower case letters are for 'trans' orientation base-pairs. -> The line labeled 'struc' represents the base-pair locations. A pair of '(' and ')' represent the base-pair that was identified in the first stage,while '<' and '>' represent the base-pair that was identified in the second stage. -> A dot in the sequence represents the breakage location of the original sequence due to presentation of multiple strands in the query motif.An '-' symbol represents a gap in the sequence. --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Alignment Score: 8.200 Aligning: Query: 1X8W_A:223-227_247-250 Target: 4GXY_A:76-80_148-153 iso .*......*... edge .w......h... struc .(......)... CUAA-G.UA-UG * | |. * | GUGACG.GAGUC struc .(......)... edge .w......h... iso .*......*... Alignment Score: 9.800 Aligning: Query: 1X8W_A:247-250_223-227 Target: 4IOA_X:1431-1435_1593-1597 iso ..*....*... edge ..h....w... struc ..(....)... U-AUG.CUAAG | *||.|*|| UGAUG.CUAAA struc ..(....)... edge ..h....w... iso ..*....*... Alignment Score: 9.400 Aligning: Query: 1X8W_A:223-227_247-250 Target: 2QBG_B:1437-1440_1551-1555 iso .*.....*.. edge .w.....h.. struc .(.....).. CUAAG.UAUG |*| . *|| CUAUA.AAUG struc .(.....).. edge .w.....h.. iso .*.....*.. Alignment Score: 8.200 Aligning: Query: 1X8W_A:223-227_247-250 Target: 4GMA_Z:86-90_153-158 iso .*......*.... edge .w......h.... struc .(......).... CUAAG.U-AUG-- * ||. * | GUGAG.CGA-GCC struc .(......).... edge .w......h.... iso .*......*.... Alignment Score: 9.000 Aligning: Query: 1X8W_A:223-227_247-250 Target: 3Q1Q_C:44-48_32-35 iso .*.....*.. edge .w.....h.. struc .(.....).. CUAAG.UAUG |*|||.|*|| CUAAG.UAUG struc .(.....).. edge .w.....h.. iso .*.....*.. Alignment Score: 7.600 Aligning: Query: 1X8W_A:223-227_247-250 Target: 3KTW_C:224-227_193-199 iso .*......*... edge .w......h... struc .(......)... CUAAG.U-AUG- * |. * GUGCG.GGAACC struc .(......)... edge .w......h... iso .*......*...